HOME WEB NEWS IMAGES CLASSIFIEDS YELLOW PAGESPOLLS - SURVEYS WIKI COUNTRIES PHOTOS US UK INDIA
Cities Stocks Weather Movies Coupons Travel Blogs Health Horoscope Maps ASIA EUROPE Classifieds Yellow Pages
|
"Neoplastic" redirects here. For Dutch artistic movement, see De Stijl.
| Neoplasm Classification & external resources | |
| ICD-10 | C00.-D48. |
|---|---|
| ICD-9 | 140-239.99 |
| DiseasesDB | 28841 |
| MedlinePlus | 001310. |
| MeSH | D009369 |
Neoplasia (new growth in Greek) is the abnormal proliferation of cells in a tissue or organ, resulting in a neoplasm.
Some sources consider a neoplasm to be synonymous with a tumor.Pancreas Cancer: Glossary of Terms. Retrieved on 2008-01-08.
Other sources make a distinction, stating that a neoplasm that forms a distinct mass is a tumor.[citation needed] Other neoplasms, those that form no mass, include cervical intraepithelial neoplasia, anal intraepithelial neoplasia, and leukemia.
The structure of a neoplasm is less organized than that of the surrounding tissue.What is neoplasm? Find the definition for neoplasm at WebMD. Retrieved on 2008-01-08.
Contents |
A neoplasm can be benign, or potentially or frankly malignant. Cancer - Activity 1 - Glossary, page 4 of 5. Retrieved on 2008-01-08.
A neoplasm can be defined as an uncontrolled and progressive growth.n_03/12561445 at Dorland\'s Medical Dictionary
Other definitions are sometimes used. The definition of the British oncologist R.A. Willis is widely cited:
| “ | A neoplasm is an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissues, and persists in the same excessive manner after cessation of the stimulus which evoked the change.Willis RA: The Spread of Tumors in the Human Body. London, Butterworth & Co, 1952 | ” |
Neoplastic tumors often contain more than one type of cell, but their initiation and continued growth is usually dependent on a single population of neoplastic cells. These cells are clonal - that is, they are descended from a single progenitor cell.
The neoplastic cells typically bear common genetic or epigenetic abnormalities which are not seen in the non-neoplastic stromal cells and blood-vessel forming cells, whose growth is dependent on molecular stimuli from the neoplastic cells.
The demonstration of clonality is now considered by many to be necessary (though not sufficient) to define a cellular proliferation as neoplastic.Lee ES, Locker J, Nalesnik M, et al (1995). "The association of Epstein-Barr virus with smooth-muscle tumors occurring after organ transplantation". N. Engl. J. Med. 332 (1): 19–25. PMID 7990861.
This article is licensed under the GNU Free Documentation License. It uses material from Wikipedia
